| 10.05.2010 | 09:30 | Sibir Novosibirsk | - | Krylia Sovetov | 4:1 (2:1) | |
| 12:00 | Spartak Vladikavkaz | - | Spartak Moskva | 5:2 (2:2) | ||
| 12:00 | CSKA Moskva | - | Terek Grozny | 4:1 (0:1) | ||
| 14:15 | FK Amkar Perm | - | Zenit St. Petersburg | 0:2 (0:0) | ||
| 16:30 | FK Rostov | - | Rubin Kazan | 0:2 (0:0) | ||
| 11.05.2010 | 14:00 | FK Saturn | - | FK Tom Tomsk | 1:2 (0:0) | |
| 16:15 | Spartak Nalchik | - | Lokomotiv Moskva | 1:1 (1:1) | ||
| 18:30 | Anzhi Makhachkala | - | Dinamo Moskva | 1:1 (1:1) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Zenit St. Petersburg | 10 | 7 | 3 | 0 | 13:3 | 10 | 24 |
| 2 |
|
CSKA Moskva | 10 | 6 | 2 | 2 | 18:9 | 9 | 20 |
| 3 |
|
Rubin Kazan | 10 | 5 | 5 | 0 | 9:2 | 7 | 20 |
| 4 |
|
Spartak Nalchik | 10 | 5 | 4 | 1 | 14:8 | 6 | 19 |
| 5 |
|
Spartak Moskva | 10 | 4 | 4 | 2 | 14:11 | 3 | 16 |
| 6 |
|
FK Tom Tomsk | 10 | 4 | 3 | 3 | 13:12 | 1 | 15 |
| 7 |
|
FK Rostov | 10 | 4 | 1 | 5 | 9:15 | -6 | 13 |
| 8 |
|
Lokomotiv Moskva | 10 | 3 | 3 | 4 | 11:11 | 0 | 12 |
| 9 |
|
Spartak Vladikavkaz | 10 | 3 | 3 | 4 | 12:13 | -1 | 12 |
| 10 |
|
Terek Grozny | 10 | 2 | 5 | 3 | 9:10 | -1 | 11 |
| 11 |
|
Dinamo Moskva | 10 | 2 | 5 | 3 | 8:9 | -1 | 11 |
| 12 |
|
Anzhi Makhachkala | 10 | 2 | 4 | 4 | 9:11 | -2 | 10 |
| 13 |
|
FK Amkar Perm | 10 | 2 | 3 | 5 | 7:11 | -4 | 9 |
| 14 |
|
Krylia Sovetov | 10 | 2 | 2 | 6 | 7:16 | -9 | 8 |
| 15 |
|
FK Saturn | 10 | 1 | 4 | 5 | 5:9 | -4 | 7 |
| 16 |
|
Sibir Novosibirsk | 10 | 2 | 1 | 7 | 12:20 | -8 | 7 |
| Champions League | |
| Champions League Quali. | |
| Europa League | |
| Abstieg |