| 18/02/2022 | 15:30 | Arda Kardzhali | - | Botev Plovdiv | 0:2 (0:0) | |
| 19/02/2022 | 13:00 | Levski Sofia | - | Lokomotiv Plovdiv | 2:1 (2:1) | |
| 15:30 | Botev Vratsa | - | CSKA 1948 Sofia | 0:4 (0:3) | ||
| 20/02/2022 | 10:45 | Tsarsko Selo Sofia | - | PFC Beroe | 1:2 (1:0) | |
| 13:15 | Cherno More Varna | - | PFC Ludogorets Razgrad | 1:2 (0:2) | ||
| 15:45 | Slavia Sofia | - | CSKA Sofia | 2:3 (0:0) | ||
| 21/02/2022 | 15:30 | Pirin Blagoevgrad | - | Lokomotiv Sofia | 2:1 (1:0) |
| » Tables | Home | Away | First round | Second round |
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
PFC Ludogorets Razgrad | 20 | 16 | 0 | 4 | 52:19 | 33 | 48 |
| 2 |
|
CSKA Sofia | 20 | 13 | 5 | 2 | 34:21 | 13 | 44 |
| 3 |
|
Botev Plovdiv | 20 | 10 | 5 | 5 | 25:21 | 4 | 35 |
| 4 |
|
Cherno More Varna | 20 | 8 | 8 | 4 | 23:15 | 8 | 32 |
| 5 |
|
Slavia Sofia | 20 | 7 | 8 | 5 | 24:20 | 4 | 29 |
| 6 |
|
Levski Sofia | 20 | 8 | 5 | 7 | 24:23 | 1 | 29 |
| 7 |
|
PFC Beroe | 20 | 8 | 4 | 8 | 21:21 | 0 | 28 |
| 8 |
|
Lokomotiv Plovdiv | 20 | 6 | 7 | 7 | 23:24 | -1 | 25 |
| 9 |
|
CSKA 1948 Sofia | 20 | 6 | 4 | 10 | 28:32 | -4 | 22 |
| 10 |
|
Arda Kardzhali | 20 | 5 | 7 | 8 | 21:29 | -8 | 22 |
| 11 |
|
Pirin Blagoevgrad | 20 | 5 | 4 | 11 | 29:36 | -7 | 19 |
| 12 |
|
Botev Vratsa | 20 | 4 | 7 | 9 | 20:32 | -12 | 19 |
| 13 |
|
Lokomotiv Sofia | 20 | 4 | 7 | 9 | 19:32 | -13 | 19 |
| 14 |
|
Tsarsko Selo Sofia | 20 | 2 | 5 | 13 | 12:30 | -18 | 11 |
| Playoffs | |
| Playoffs | |
| Playoffs |