| 21/11/2020 | 11:00 | FK Krasnodar | - | FK Tambov | 1:0 (1:0) | |
| 13:30 | Akhmat Grozny | - | Zenit St. Petersburg | 2:2 (1:1) | ||
| 16:00 | Lokomotiv Moskva | - | Arsenal Tula | 1:0 (0:0) | ||
| 16:00 | Spartak Moskva | - | Dinamo Moskva | 1:1 (0:0) | ||
| 22/11/2020 | 11:00 | CSKA Moskva | - | FK Sochi | 1:1 (1:1) | |
| 13:30 | Rotor Volgograd | - | FK Ural | 0:0 (0:0) | ||
| 16:00 | Rubin Kazan | - | FK Rostov | 0:2 (0:0) | ||
| 23/11/2020 | 14:00 | FK Ufa | - | FK Khimki | 1:2 (0:2) |
| » Tables | Home | Away | First round | Second round |
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
CSKA Moskva | 15 | 10 | 2 | 3 | 28:11 | 17 | 32 |
| 2 |
|
Zenit St. Petersburg | 15 | 9 | 4 | 2 | 32:12 | 20 | 31 |
| 3 |
|
Spartak Moskva | 15 | 8 | 5 | 2 | 25:16 | 9 | 29 |
| 4 |
|
Dinamo Moskva | 15 | 8 | 3 | 4 | 21:12 | 9 | 27 |
| 5 |
|
FK Rostov | 15 | 8 | 2 | 5 | 18:15 | 3 | 26 |
| 6 |
|
Akhmat Grozny | 15 | 7 | 3 | 5 | 19:18 | 1 | 24 |
| 7 |
|
Lokomotiv Moskva | 15 | 7 | 3 | 5 | 16:16 | 0 | 24 |
| 8 |
|
FK Sochi | 15 | 6 | 6 | 3 | 23:21 | 2 | 24 |
| 9 |
|
FK Krasnodar | 15 | 6 | 3 | 6 | 24:18 | 6 | 21 |
| 10 |
|
Rubin Kazan | 15 | 6 | 3 | 6 | 21:22 | -1 | 21 |
| 11 |
|
FK Ural | 15 | 3 | 7 | 5 | 11:15 | -4 | 16 |
| 12 |
|
FK Khimki | 15 | 4 | 3 | 8 | 17:26 | -9 | 15 |
| 13 |
|
Arsenal Tula | 15 | 3 | 4 | 8 | 17:27 | -10 | 13 |
| 14 |
|
FK Tambov | 15 | 3 | 3 | 9 | 11:18 | -7 | 12 |
| 15 |
|
Rotor Volgograd | 15 | 1 | 5 | 9 | 7:23 | -16 | 8 |
| 16 |
|
FK Ufa | 15 | 1 | 4 | 10 | 9:29 | -20 | 7 |
| Champions League | |
| Champions League Quali. | |
| Europa League Quali. | |
| Playoffs | |
| Relegation |