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response to lipopolysaccharide

Term Information

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Accession
GO:0032496
Name
response to lipopolysaccharide
Ontology
biological_process
Synonyms
response to LPS, response to endotoxin
Alternate IDs
None
Definition
Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria. Source: GOC:add, ISBN:0721601464
Comment
None
History
See term history for GO:0032496 at QuickGO
Chem. react.
None
Subset
None
Link to all genes and gene products annotated to response to lipopolysaccharide (excluding "regulates").
Link to all direct and indirect annotations to response to lipopolysaccharide (excluding "regulates").
Link to all direct and indirect annotations download (limited to first 10,000) for response to lipopolysaccharide (excluding "regulates").
Include "regulates"
For more information, please see the ontology relation documentation.

Filter results

Total annotations: 4004
User filters
+isa_partof_closure: GO:0032496
Your search is pinned to these filters
−document_category: annotation

Ontology (aspect)

(3902)P
(102)F

Organism

(4003)Eukaryota
(3995)Metazoa
(3921)Vertebrata
(3420)Mammalia
(861)Rattus norvegicus
(772)Mus musculus
(529)Homo sapiens
(273)Bos taurus
(264)Sus scrofa
(227)Canis lupus familiaris
(205)Gallus gallus
(90)Danio rerio
(76)Macaca mulatta
(65)Equus caballus
(64)Gorilla gorilla gorilla
(59)Pan troglodytes
(54)Felis catus
(46)Monodelphis domestica
(46)Ornithorhynchus anatinus
(35)Oryzias latipes
(35)Xenopus laevis
(25)Strongylocentrotus purpuratus
(24)Anolis carolinensis
(24)Lepisosteus oculatus

Type

(2902)protein
(852)gene
(81)miRNA_gene
(79)protein_coding_gene
(40)gene_product
(24)pre_miRNA
(15)miRNA
(5)protein_complex
(2)lncRNA_gene
(1)antisense_lncRNA_gene
(1)gene_segment
(1)lncRNA
(1)tRNA_gene

Evidence

(1881)similarity evidence used in manual assertion
(1173)evidence used in automatic assertion
(1024)biological aspect of ancestor evidence used in manual assertion
(932)experimental evidence
(519)sequence orthology evidence used in manual assertion
(375)direct assay evidence used in manual assertion
(337)sequence similarity evidence used in manual assertion
(298)expression pattern evidence used in manual assertion
(220)mutant phenotype evidence used in manual assertion
(39)genetic interaction evidence used in manual assertion
(11)author statement supported by traceable reference used in manual assertion
(4)author statement without traceable support used in manual assertion
(3)curator inference used in manual assertion
(1)sequence alignment evidence used in manual assertion

GO class (including "regulates")

The top (13) redundant fields are not shown
(2541)cellular process
(2541)cellular response to biotic stimulus
(2541)cellular response to chemical stimulus
(2541)cellular response to lipid
(2541)cellular response to lipopolysaccharide
(2541)cellular response to molecule of bacterial origin
(2541)cellular response to oxygen-containing compound
(2541)cellular response to stimulus
(512)biological regulation
(512)cell communication
(512)cell surface receptor signaling pathway

GO class (excluding "regulates")

The top (13) redundant fields are not shown
(2541)cellular process
(2541)cellular response to biotic stimulus
(2541)cellular response to chemical stimulus
(2541)cellular response to lipid
(2541)cellular response to lipopolysaccharide
(2541)cellular response to molecule of bacterial origin
(2541)cellular response to oxygen-containing compound
(2541)cellular response to stimulus
(512)biological regulation
(512)regulation of biological process
(512)regulation of cellular process

GO class (direct)

(2029)cellular response to lipopolysaccharide
(1358)response to lipopolysaccharide
(393)lipopolysaccharide-mediated signaling pathway
(105)detection of lipopolysaccharide
(102)lipopolysaccharide immune receptor activity
(17)tolerance induction to lipopolysaccharide

Annotation qualifier

(7)not

Annotation extension

(141)anatomical entity
(141)anatomical structure
(141)biological entity
(141)cell
(141)connected anatomical structure
(141)eukaryotic cell
(141)material anatomical entity
(126)disconnected anatomical group
(124)non-connected functional system
(122)hematopoietic cell
(122)immune system
(122)leukocyte
(122)motile cell
(122)nucleate cell
(120)mononuclear cell
(120)single nucleate cell
(103)stuff accumulating cell
(102)defensive cell
(102)mononuclear phagocyte
(102)phagocyte
(102)phagocyte (sensu Vertebrata)
(96)myeloid cell
(96)myeloid leukocyte
(94)professional antigen presenting cell

Contributor

(1140)GO_Central
(1124)Ensembl
(689)RGD
(358)UniProt
(319)MGI
(166)AgBase
(74)BHF-UCL
(37)ARUK-UCL
(32)ZFIN
(27)RNAcentral
(20)GOC
(7)ComplexPortal
(3)FlyBase
(3)ParkinsonsUK-UCL
(2)TAIR
(2)dictyBase
(1)CAFA

PANTHER family

(180)small inducible cytokine a pthr12015
(176)toll-like receptor pthr24365
(156)interleukin-1 family member pthr10078
(150)t-lymphocyte activation antigen pthr25466
(111)alpha-defensin 1 pthr11876
(102)interleukin-1 receptor-associated kinase pthr24419
(94)nitric oxide synthase-related pthr19384
(93)md-1, md-2 - related pthr15218
(92)tnfaip3-interacting protein coiled coil family member pthr31882
(69)bactericidal permeability-increasing bpi protein-related pthr10504
(50)nuclear factor nf-kappa-b protein pthr24169
(49)monocyte differentiation antigen cd14 pthr10630
(46)tnf receptor associated factor pthr10131
(44)high mobility group protein dsp1 pthr48112
(43)mitogen-activated protein kinase pthr24055
(40)nuclear hormone receptor pthr24082
(37)g-protein coupled receptor family 1 member pthr11866
(32)sugar kinase pthr10196
(30)tyrosine-protein kinase pthr24418
(29)s100 calcium-binding protein pthr11639
(28)scavenger receptor class b type-1 sr-b1 pthr11923
(28)tumor necrosis factor family member pthr11471
(27)slit related leucine-rich repeat neuronal protein pthr24373
(25)tir domain-containing adapter molecule 1 pthr47230
Total annotations: 4004; showing: 1-10
Results count  
 
Gene/productGene/product nameAnnotation qualifierGO class (direct)Annotation extensionContributorOrganismEvidenceEvidence withPANTHER familyTypeIsoformReferenceDate
LOC101157707C-X-C motif chemokine 6-likecellular response to lipopolysaccharideGO_CentralOryzias latipesIBAPANTHER:PTN002564680
RGD:708540 		small inducible cytokine a pthr12015proteinGO_REF:000003320171117
TNIP1TNFAIP3 interacting protein 1cellular response to lipopolysaccharideGO_CentralSus scrofaIBAPANTHER:PTN001590884
UniProtKB:Q96KP6
MGI:MGI:2386643		tnfaip3-interacting protein coiled coil family member pthr31882proteinGO_REF:000003320210614
TNIP3TNFAIP3 interacting protein 3cellular response to lipopolysaccharideGO_CentralEquus caballusIBAPANTHER:PTN001590884
UniProtKB:Q96KP6
MGI:MGI:2386643		tnfaip3-interacting protein coiled coil family member pthr31882proteinGO_REF:000003320210614
IL36RNInterleukin-1cellular response to lipopolysaccharideGO_CentralMacaca mulattaIBAPANTHER:PTN002560644
RGD:2891
RGD:2889		interleukin-1 family member pthr10078proteinGO_REF:000003320240918
LOC110255300Multifunctional fusion proteincellular response to lipopolysaccharideGO_CentralSus scrofaIBAPANTHER:PTN002560644
RGD:2891
RGD:2889		interleukin-1 family member pthr10078proteinGO_REF:000003320240918
LBPLipopolysaccharide-binding proteinlipopolysaccharide-mediated signaling pathwayGO_CentralSus scrofaIBAPANTHER:PTN002471180
UniProtKB:P18428		bactericidal permeability-increasing bpi protein-related pthr10504proteinGO_REF:000003320190426
DEFA4Mammalian defensins domain-containing proteincellular response to lipopolysaccharideGO_CentralMacaca mulattaIBAPANTHER:PTN002275316
MGI:MGI:94883 		alpha-defensin 1 pthr11876proteinGO_REF:000003320170608
IRAK2Interleukin-1 receptor-associated kinase-like 2lipopolysaccharide-mediated signaling pathwayGO_CentralSus scrofaIBAPANTHER:PTN000701353
MGI:MGI:107420 		interleukin-1 receptor-associated kinase pthr24419proteinGO_REF:000003320240726
IRAK4Interleukin-1 receptor-associated kinase 4lipopolysaccharide-mediated signaling pathwayGO_CentralFelis catusIBAPANTHER:PTN000701353
MGI:MGI:107420 		interleukin-1 receptor-associated kinase pthr24419proteinGO_REF:000003320240726
LOC101094096C-X-C motif chemokinecellular response to lipopolysaccharideGO_CentralFelis catusIBAPANTHER:PTN002564680
RGD:708540 		small inducible cytokine a pthr12015proteinGO_REF:000003320171117
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Graph of GO:0032496 from QuickGO

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Additional internal viewing options
Parents of response to lipopolysaccharide (GO:0032496)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
response to lipopolysaccharide [is_a relation] is_a  response to lipid (GO:0033993)
response to lipopolysaccharide [is_a relation] is_a  response to oxygen-containing compound (GO:1901700)
response to lipopolysaccharide [is_a relation] is_a  response to molecule of bacterial origin (GO:0002237)
response to lipopolysaccharide [RO:0004009 relation] RO:0004009  lipopolysaccharide (CHEBI:16412)
Children of response to lipopolysaccharide (GO:0032496)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
cellular response to lipopolysaccharide (GO:0071222) [is_a relation] is_a  response to lipopolysaccharide
detection of lipopolysaccharide (GO:0032497) [is_a relation] is_a  response to lipopolysaccharide
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