Fig. 4
From: Spatiotemporal diversity in molecular and functional abnormalities in the mdx dystrophic brain
Dystrophic genome-scale metabolic modelling. A Reaction enrichment analysis. Fold changes in the reaction flux between mdx and C57Bl/10 at 10d and 10w. The reactions are sorted by pathway, and the pathways associated with each reaction are indicated. B Fold changes in pathway flux between the cerebra of mdx and C57Bl/10 mice at 10d and 10w. The reactions are grouped by pathways, indicating the pathways associated with each reaction. For A and B, the upregulated and downregulated reactions are shown in red and blue, respectively; “_b” and “_f” represent backwards and forward reactions, respectively; compartments: (e): Extracellular, (x): Peroxisome, (m): Mitochondria, (c): Cytosol, (l): Lysosome, (r): Endoplasmic reticulum, (g): Golgi apparatus, (n): Nucleus, (i): Inner mitochondria