| 14/05/2022 | 18:00 | AC Ajaccio | - | Toulouse FC | 1:0 (1:0) | |
| 18:00 | AJ Auxerre | - | Amiens SC | 2:1 (1:0) | ||
| 18:00 | AS Nancy Lorraine | - | Pau FC | 2:3 (2:3) | ||
| 18:00 | EA Guingamp | - | Havre AC | 2:1 (1:1) | ||
| 18:00 | Chamois Niortais | - | Valenciennes FC | 1:2 (1:1) | ||
| 18:00 | Paris FC | - | Grenoble Foot 38 | 2:0 (0:0) | ||
| 18:00 | FC Sochaux | - | Dijon FCO | 2:2 (1:0) | ||
| 18:00 | Nîmes Olympique | - | SC Bastia | 0:2 (0:0) | ||
| 18:00 | Rodez AF | - | SM Caen | 2:0 (0:0) | ||
| 18:00 | US Quevilly-Rouen | - | USL Dunkerque | 3:1 (1:1) |
| » Tables | First round | Second round |
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Toulouse FC | 38 | 23 | 10 | 5 | 82:33 | 49 | 79 |
| 2 |
|
AC Ajaccio | 38 | 22 | 9 | 7 | 39:19 | 20 | 75 |
| 3 |
|
AJ Auxerre | 38 | 21 | 11 | 6 | 61:39 | 22 | 74 |
| 4 |
|
Paris FC | 38 | 20 | 10 | 8 | 54:35 | 19 | 70 |
| 5 |
|
FC Sochaux | 38 | 19 | 11 | 8 | 47:34 | 13 | 68 |
| 6 |
|
EA Guingamp | 38 | 15 | 13 | 10 | 52:48 | 4 | 58 |
| 7 |
|
SM Caen | 38 | 13 | 11 | 14 | 51:42 | 9 | 50 |
| 8 |
|
Havre AC | 38 | 13 | 11 | 14 | 38:41 | -3 | 50 |
| 9 |
|
Nîmes Olympique | 38 | 14 | 7 | 17 | 44:51 | -7 | 49 |
| 10 |
|
Pau FC | 38 | 14 | 7 | 17 | 41:49 | -8 | 49 |
| 11 |
|
Dijon FCO | 38 | 13 | 8 | 17 | 48:53 | -5 | 47 |
| 12 |
|
SC Bastia | 38 | 10 | 16 | 12 | 38:36 | 2 | 46 |
| 13 |
|
Chamois Niortais | 38 | 12 | 10 | 16 | 39:42 | -3 | 46 |
| 14 |
|
Amiens SC | 38 | 9 | 17 | 12 | 43:41 | 2 | 44 |
| 15 |
|
Grenoble Foot 38 | 38 | 12 | 8 | 18 | 32:44 | -12 | 44 |
| 16 |
|
Valenciennes FC | 38 | 10 | 14 | 14 | 34:47 | -13 | 44 |
| 17 |
|
Rodez AF | 38 | 10 | 13 | 15 | 32:42 | -10 | 43 |
| 18 |
|
US Quevilly-Rouen | 38 | 10 | 10 | 18 | 33:50 | -17 | 40 |
| 19 |
|
USL Dunkerque | 38 | 8 | 7 | 23 | 28:53 | -25 | 31 |
| 20 |
|
AS Nancy Lorraine | 38 | 6 | 9 | 23 | 32:69 | -37 | 27 |
| Promotion | |
| Playoffs | |
| Playoffs | |
| Relegation |