| 15/05/2016 | 11:00 | Real Betis B | - | CF Villanovense | 4:1 (2:1) | |
| 17:00 | Mérida AD | - | UD Almería B | 3:3 (0:1) | ||
| 17:00 | FC Jumilla | - | Sevilla Atlético | 0:0 (0:0) | ||
| 17:00 | UCAM Murcia CF | - | RB Linense | 3:1 (1:1) | ||
| 17:00 | Real Jaén | - | Cádiz CF | 0:1 (0:0) | ||
| 17:00 | Recreativo Huelva | - | Linares Deportivo | 0:0 (0:0) | ||
| 17:00 | FC Cartagena | - | CD San Roque de Lepe | 1:1 (1:0) | ||
| 17:00 | Granada CF B | - | UD Melilla | 4:0 (0:0) | ||
| 17:00 | Algeciras CF | - | Real Murcia | 1:2 (1:1) | ||
| 17:00 | Marbella FC | - | La Hoya Lorca CF | 1:1 (0:0) |
| » Tables | First round | Second round |
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
UCAM Murcia CF | 38 | 22 | 11 | 5 | 46:17 | 29 | 77 |
| 2 |
|
Real Murcia | 38 | 21 | 8 | 9 | 56:30 | 26 | 71 |
| 3 |
|
Sevilla Atlético | 38 | 17 | 17 | 4 | 53:31 | 22 | 68 |
| 4 |
|
Cádiz CF | 38 | 17 | 12 | 9 | 53:31 | 22 | 63 |
| 5 |
|
Granada CF B | 38 | 15 | 13 | 10 | 56:40 | 16 | 58 |
| 6 |
|
La Hoya Lorca CF | 38 | 14 | 14 | 10 | 43:41 | 2 | 56 |
| 7 |
|
FC Cartagena | 38 | 12 | 17 | 9 | 40:35 | 5 | 53 |
| 8 |
|
Mérida AD | 38 | 12 | 16 | 10 | 39:41 | -2 | 52 |
| 9 |
|
UD Melilla | 38 | 12 | 13 | 13 | 34:44 | -10 | 49 |
| 10 |
|
Real Jaén | 38 | 14 | 6 | 18 | 46:37 | 9 | 48 |
| 11 |
|
RB Linense | 38 | 13 | 9 | 16 | 47:51 | -4 | 48 |
| 12 |
|
CF Villanovense | 38 | 13 | 8 | 17 | 49:56 | -7 | 47 |
| 13 |
|
Recreativo Huelva | 38 | 11 | 12 | 15 | 27:38 | -11 | 45 |
| 14 |
|
Marbella FC | 38 | 9 | 18 | 11 | 46:47 | -1 | 45 |
| 15 |
|
FC Jumilla | 38 | 11 | 10 | 17 | 36:57 | -21 | 43 |
| 16 |
|
Linares Deportivo | 38 | 9 | 16 | 13 | 39:46 | -7 | 43 |
| 17 |
|
Real Betis B | 38 | 10 | 11 | 17 | 47:53 | -6 | 41 |
| 18 |
|
Algeciras CF | 38 | 11 | 8 | 19 | 28:48 | -20 | 41 |
| 19 |
|
CD San Roque de Lepe | 38 | 6 | 21 | 11 | 42:55 | -13 | 39 |
| 20 |
|
UD Almería B | 38 | 6 | 10 | 22 | 26:55 | -29 | 28 |
| Playoffs | |
| Playoffs | |
| Playoffs | |
| Relegation |