| 02/10/2021 | 17:00 | SD Compostela | - | Bergantiños FC | 1:1 (1:0) | |
| 17:00 | UP Langreo | - | Gimnástica Segoviana | 1:1 (0:0) | ||
| 03/10/2021 | 11:00 | CD Móstoles URJC | - | CD Leganés B | 3:3 (1:2) | |
| 11:00 | Unión Club Ceares | - | UD Llanera | 0:2 (0:1) | ||
| 16:00 | Pontevedra CF | - | CD Arenteiro | 2:2 (0:2) | ||
| 16:00 | CD Cristo Atlético | - | CDA Navalcarnero | 3:0 (1:0) | ||
| 16:00 | Real Avilés | - | Unión Adarve | 2:1 (2:0) | ||
| 16:00 | Salamanca CF UDS | - | Marino de Luanco | 0:2 (0:1) | ||
| 18:00 | Arosa SC | - | Coruxo FC | 0:1 (0:0) |
| » Tables | Home | Away | First round | Second round |
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Unión Adarve | 5 | 3 | 1 | 1 | 11:5 | 6 | 10 |
| 2 |
|
SD Compostela | 5 | 2 | 3 | 0 | 9:4 | 5 | 9 |
| 3 |
|
UP Langreo | 5 | 2 | 3 | 0 | 9:5 | 4 | 9 |
| 4 |
|
Real Avilés | 5 | 2 | 3 | 0 | 6:4 | 2 | 9 |
| 5 |
|
CD Leganés B | 5 | 2 | 2 | 1 | 8:6 | 2 | 8 |
| 6 |
|
Gimnástica Segoviana | 5 | 2 | 2 | 1 | 8:7 | 1 | 8 |
| 7 |
|
CD Cristo Atlético | 5 | 2 | 1 | 2 | 7:7 | 0 | 7 |
| 8 |
|
Arosa SC | 5 | 2 | 1 | 2 | 3:3 | 0 | 7 |
| 9 |
|
Salamanca CF UDS | 5 | 2 | 1 | 2 | 2:3 | -1 | 7 |
| 10 |
|
Marino de Luanco | 5 | 2 | 0 | 3 | 9:7 | 2 | 6 |
| 11 |
|
UD Llanera | 5 | 1 | 3 | 1 | 5:5 | 0 | 6 |
| 12 |
|
CDA Navalcarnero | 5 | 2 | 0 | 3 | 4:9 | -5 | 6 |
| 13 |
|
CD Móstoles URJC | 5 | 1 | 2 | 2 | 8:10 | -2 | 5 |
| 14 |
|
CD Arenteiro | 5 | 1 | 2 | 2 | 4:6 | -2 | 5 |
| 15 |
|
Pontevedra CF | 5 | 0 | 4 | 1 | 8:9 | -1 | 4 |
| 16 |
|
Coruxo FC | 5 | 1 | 1 | 3 | 3:5 | -2 | 4 |
| 17 |
|
Bergantiños FC | 5 | 0 | 4 | 1 | 3:6 | -3 | 4 |
| 18 |
|
Unión Club Ceares | 5 | 1 | 1 | 3 | 3:9 | -6 | 4 |
| Promotion | |
| Playoffs | |
| Playoffs | |
| Relegation |