| 19/05/2001 | 15:00 | Charlton Athletic | - | Liverpool FC | 0:4 (0:0) | |
| 15:00 | Coventry City | - | Bradford City | 0:0 (0:0) | ||
| 15:00 | Derby County | - | Ipswich Town | 1:1 (1:0) | ||
| 15:00 | Everton FC | - | Sunderland AFC | 2:2 (1:1) | ||
| 15:00 | Leeds United | - | Leicester City | 3:1 (1:1) | ||
| 15:00 | Manchester City | - | Chelsea FC | 1:2 (1:1) | ||
| 15:00 | Middlesbrough FC | - | West Ham United | 2:1 (2:1) | ||
| 15:00 | Newcastle United | - | Aston Villa | 3:0 (2:0) | ||
| 15:00 | Southampton FC | - | Arsenal FC | 3:2 (0:1) | ||
| 15:00 | Tottenham Hotspur | - | Manchester United | 3:1 (1:1) |
| » Tables | Home | Away | First round | Second round | First half | Second half |
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Manchester United | 38 | 24 | 8 | 6 | 79:31 | 48 | 80 |
| 2 |
|
Arsenal FC | 38 | 20 | 10 | 8 | 63:38 | 25 | 70 |
| 3 |
|
Liverpool FC | 38 | 20 | 9 | 9 | 71:39 | 32 | 69 |
| 4 |
|
Leeds United | 38 | 20 | 8 | 10 | 64:43 | 21 | 68 |
| 5 |
|
Ipswich Town | 38 | 20 | 6 | 12 | 57:42 | 15 | 66 |
| 6 |
|
Chelsea FC | 38 | 17 | 10 | 11 | 68:45 | 23 | 61 |
| 7 |
|
Sunderland AFC | 38 | 15 | 12 | 11 | 46:41 | 5 | 57 |
| 8 |
|
Aston Villa | 38 | 13 | 15 | 10 | 46:43 | 3 | 54 |
| 9 |
|
Charlton Athletic | 38 | 14 | 10 | 14 | 50:57 | -7 | 52 |
| 10 |
|
Southampton FC | 38 | 14 | 10 | 14 | 40:48 | -8 | 52 |
| 11 |
|
Newcastle United | 38 | 14 | 9 | 15 | 44:50 | -6 | 51 |
| 12 |
|
Tottenham Hotspur | 38 | 13 | 10 | 15 | 47:54 | -7 | 49 |
| 13 |
|
Leicester City | 38 | 14 | 6 | 18 | 39:51 | -12 | 48 |
| 14 |
|
Middlesbrough FC | 38 | 9 | 15 | 14 | 44:44 | 0 | 42 |
| 15 |
|
West Ham United | 38 | 10 | 12 | 16 | 45:50 | -5 | 42 |
| 16 |
|
Everton FC | 38 | 11 | 9 | 18 | 45:59 | -14 | 42 |
| 17 |
|
Derby County | 38 | 10 | 12 | 16 | 37:59 | -22 | 42 |
| 18 |
|
Manchester City | 38 | 8 | 10 | 20 | 41:65 | -24 | 34 |
| 19 |
|
Coventry City | 38 | 8 | 10 | 20 | 36:63 | -27 | 34 |
| 20 |
|
Bradford City | 38 | 5 | 11 | 22 | 30:70 | -40 | 26 |