| 1st(1st leg) | Stade Brestois 29 | - | Paris Saint-Germain | 0:3 (0:2) | ||
| 2nd (2nd leg) | Paris Saint-Germain | - | Stade Brestois 29 | 7:0 (2:0) | ||
| 1st(1st leg): 11/02/2025 17:45 | 2nd (2nd leg): 19/02/2025 20:00 | Winner: Paris Saint-Germain | ||||
| 1st(1st leg) | Manchester City | - | Real Madrid | 2:3 (1:0) | ||
| 2nd (2nd leg) | Real Madrid | - | Manchester City | 3:1 (2:0) | ||
| 1st(1st leg): 11/02/2025 20:00 | 2nd (2nd leg): 19/02/2025 20:00 | Winner: Real Madrid | ||||
| 1st(1st leg) | Juventus | - | PSV Eindhoven | 2:1 (1:0) | ||
| 2nd (2nd leg) | PSV Eindhoven | - | Juventus | 3:1 (0:0, 2:1) aet | ||
| 1st(1st leg): 11/02/2025 20:00 | 2nd (2nd leg): 19/02/2025 20:00 | Winner: PSV Eindhoven | ||||
| 1st(1st leg) | Sporting CP | - | Borussia Dortmund | 0:3 (0:0) | ||
| 2nd (2nd leg) | Borussia Dortmund | - | Sporting CP | 0:0 (0:0) | ||
| 1st(1st leg): 11/02/2025 20:00 | 2nd (2nd leg): 19/02/2025 17:45 | Winner: Borussia Dortmund | ||||
| 1st(1st leg) | Club Brugge KV | - | Atalanta | 2:1 (1:1) | ||
| 2nd (2nd leg) | Atalanta | - | Club Brugge KV | 1:3 (0:3) | ||
| 1st(1st leg): 12/02/2025 17:45 | 2nd (2nd leg): 18/02/2025 20:00 | Winner: Club Brugge KV | ||||
| 1st(1st leg) | AS Monaco | - | SL Benfica | 0:1 (0:0) | ||
| 2nd (2nd leg) | SL Benfica | - | AS Monaco | 3:3 (1:1) | ||
| 1st(1st leg): 12/02/2025 20:00 | 2nd (2nd leg): 18/02/2025 20:00 | Winner: SL Benfica | ||||
| 1st(1st leg) | Celtic FC | - | Bayern München | 1:2 (0:1) | ||
| 2nd (2nd leg) | Bayern München | - | Celtic FC | 1:1 (0:0) | ||
| 1st(1st leg): 12/02/2025 20:00 | 2nd (2nd leg): 18/02/2025 20:00 | Winner: Bayern München | ||||
| 1st(1st leg) | Feyenoord | - | AC Milan | 1:0 (1:0) | ||
| 2nd (2nd leg) | AC Milan | - | Feyenoord | 1:1 (1:0) | ||
| 1st(1st leg): 12/02/2025 20:00 | 2nd (2nd leg): 18/02/2025 17:45 | Winner: Feyenoord | ||||